INT257280

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Context Info
Confidence 0.17
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.14
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (RBP1) cytoplasm (RBP1)
Anatomy Link Frequency
myometrium 2
RBP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 3 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
pain pelvic 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Uterine Fibroids 120 98.48 Very High Very High Very High
Rheumatoid Arthritis 24 68.72 Quite High
Apoptosis 3 67.20 Quite High
Cancer 9 5.00 Very Low Very Low Very Low
Papillomavirus Infection 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Pulmonary Fibrosis 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Leukemia 2 5.00 Very Low Very Low Very Low
Reprotox - General 1 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have previously shown that cellular retinol binding protein (CRBP-1) was down-regulated in leiomyoma tissue as compared to myometrium.6 In this study, we have demonstrated that our immortalized cell lines also show a similar threefold down-regulation of CRBP-1 mRNA expression (0·38 ± 0·14; P < 0·05) in untreated leiomyoma cells compared to myometrial cells (Table 1).
Regulation (regulation) of Transcription (expression) of CRBP-1 in myometrium associated with uterine fibroids
1) Confidence 0.17 Published 2008 Journal Clinical Endocrinology Section Body Doc Link PMC2610401 Disease Relevance 1.14 Pain Relevance 0

General Comments

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