INT257284

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Context Info
Confidence 0.23
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.12
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (DPT) extracellular region (DPT) cell adhesion (DPT)
proteinaceous extracellular matrix (DPT)
Anatomy Link Frequency
myometrium 2
DPT (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 6 5.00 Very Low Very Low Very Low
fibrosis 6 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
pain pelvic 2 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Uterine Fibroids 240 99.32 Very High Very High Very High
Papillomavirus Infection 6 79.44 Quite High
Infection 4 48.56 Quite Low
Disease 6 44.96 Quite Low
Rheumatoid Arthritis 48 5.00 Very Low Very Low Very Low
Cancer 18 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low
Pulmonary Fibrosis 4 5.00 Very Low Very Low Very Low
Adhesions 4 5.00 Very Low Very Low Very Low
Leukemia 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The immortalized cell lines were confirmed to be derived either from myometrium or leiomyoma using the specific biomarker gene array as described previously.8 Using real-time RT-PCR, expression of the genes dermatopontin, versican, TGF-?
Gene_expression (expression) of dermatopontin in myometrium associated with uterine fibroids
1) Confidence 0.23 Published 2008 Journal Clinical Endocrinology Section Body Doc Link PMC2610401 Disease Relevance 0.35 Pain Relevance 0
We further validated leiomyoma from myometrial cultures based on the molecular characteristics that distinguish leiomyoma from the normal myometrium.8 The expression of dermatopontin was markedly reduced in immortalized leiomyoma cells compared to patient matched myometrial cells (–15·2 ± 3·2-fold, P < 0·05).
Gene_expression (expression) of dermatopontin in myometrium associated with uterine fibroids
2) Confidence 0.18 Published 2008 Journal Clinical Endocrinology Section Body Doc Link PMC2610401 Disease Relevance 0.77 Pain Relevance 0

General Comments

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