INT257286

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Context Info
Confidence 0.45
First Reported 2008
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.59
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (COL4A1)
COL4A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 49 89.28 High High
Inflammation 24 5.00 Very Low Very Low Very Low
fibrosis 13 5.00 Very Low Very Low Very Low
cytokine 9 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
pain pelvic 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Uterine Fibroids 120 99.84 Very High Very High Very High
Adhesions 2 69.12 Quite High
Stress 10 11.60 Low Low
Repression 34 5.00 Very Low Very Low Very Low
Cancer 31 5.00 Very Low Very Low Very Low
INFLAMMATION 26 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 24 5.00 Very Low Very Low Very Low
Fibrosis 13 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Pulmonary Fibrosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increased levels of ACTA2 and COL4A1 mRNA were detectable after 6?
Transcription (detectable) of COL4A1
1) Confidence 0.45 Published 2011 Journal Nucleic Acids Research Section Body Doc Link PMC3017614 Disease Relevance 0 Pain Relevance 0.04
Increased levels of ACTA2 and COL4A1 mRNA were detectable after 6?
Transcription (levels) of COL4A1
2) Confidence 0.45 Published 2011 Journal Nucleic Acids Research Section Body Doc Link PMC3017614 Disease Relevance 0 Pain Relevance 0.04
Taken together, ATRA exposure reduced COL1A1 and COL4A1 mRNA expression in leiomyoma cells, approaching expression patterns comparable to myometrial cells.
Transcription (expression) of COL4A1 associated with uterine fibroids
3) Confidence 0.41 Published 2008 Journal Clinical Endocrinology Section Body Doc Link PMC2610401 Disease Relevance 0.59 Pain Relevance 0

General Comments

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