INT257319

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.04
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.62
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Lox) oxidoreductase activity (Lox) extracellular region (Lox)
proteinaceous extracellular matrix (Lox) nucleus (Lox)
Anatomy Link Frequency
kidney 2
Lox (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 2 99.52 Very High Very High Very High
cINOD 2 95.20 Very High Very High Very High
Inflammation 80 95.00 High High
fibrosis 2 72.88 Quite High
cytokine 6 12.32 Low Low
nud 6 5.00 Very Low Very Low Very Low
aspirin 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 12 100.00 Very High Very High Very High
INFLAMMATION 84 95.00 High High
Infection 30 88.08 High High
Hypotension 1 83.04 Quite High
Hyperplasia 1 74.44 Quite High
Fibrosis 3 72.88 Quite High
Hypertension 14 68.00 Quite High
Hypertrophy 5 62.16 Quite High
Apoptosis 14 61.48 Quite High
Atrophic Gastritis 38 53.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Red ginseng extracts inhibited these increments of H. pylori-stimulated 5-LOX through inactivation of c-jun phosphorylation and redox-sensitive transcriptional activation together, finally led to reduced levels of IL-8 and 5-LOX in gastric mucosal cells (Fig. 2B).
Negative_regulation (reduced) of Gene_expression (levels) of LOX
1) Confidence 0.04 Published 2010 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2872224 Disease Relevance 0.44 Pain Relevance 0.09
Red ginseng treatment was efficient in decreasing H. pylori-induced 5-LOX activities and attenuating 5-LOX expression through inactivating c-jun pathway.
Negative_regulation (attenuating) of Gene_expression (expression) of LOX
2) Confidence 0.04 Published 2010 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2872224 Disease Relevance 0.56 Pain Relevance 0.18
In the present study, a total blockade of the pro-oxidative effects of aldosterone on aortic segments and kidney was obtained only when the rats were treated with a mineralocorticoid receptor antagonist, spironolactone, which prevented oxidative stress increase, overexpression of NAD(P)H oxidase subunits and BP elevation.
Negative_regulation (prevented) of Gene_expression (overexpression) of H oxidase in kidney associated with stress and antagonist
3) Confidence 0.03 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2610641 Disease Relevance 0.62 Pain Relevance 0.09

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox