INT257345

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Context Info
Confidence 0.08
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Ncf1, Ros1) plasma membrane (Ncf1, Ros1) cell differentiation (Ros1)
cytosol (Ncf1) Golgi apparatus (Ncf1) cytoplasm (Ncf1)
Anatomy Link Frequency
smooth muscle cells 2
Ncf1 (Rattus norvegicus)
Ros1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fibrosis 2 7.92 Low Low
Inflammation 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertrophy 5 94.72 High High
Cancer 1 94.64 High High
Necrosis 1 94.40 High High
Targeted Disruption 1 67.04 Quite High
Hypertension 14 56.08 Quite High
Stroke 1 51.52 Quite High
Cardiovascular Disorder Under Development 4 50.00 Quite Low
Stress 8 14.88 Low Low
Fibrosis 3 7.92 Low Low
Coronary Heart Disease 3 7.40 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The p47phox subunit has been shown to be essential for ROS production in response to phorbol ester (PMA), AngII, thrombin, and platelet-derived growth factor in vascular smooth muscle cells (23, 24) and tumor necrosis factor alpha (TNF-?)
p47phox Positive_regulation (essential) of Gene_expression (production) of ROS in smooth muscle cells associated with necrosis and cancer
1) Confidence 0.08 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2610641 Disease Relevance 0.58 Pain Relevance 0

General Comments

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