INT257384

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Context Info
Confidence 0.14
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.17
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (C6orf25) endoplasmic reticulum (C6orf25) plasma membrane (C6orf25)
Anatomy Link Frequency
myocardium 4
C6orf25 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 12 35.16 Quite Low
cytokine 18 15.24 Low Low
analgesia 36 5.00 Very Low Very Low Very Low
anesthesia 32 5.00 Very Low Very Low Very Low
cva 32 5.00 Very Low Very Low Very Low
Inflammation 27 5.00 Very Low Very Low Very Low
Regional anesthesia 14 5.00 Very Low Very Low Very Low
epidural 12 5.00 Very Low Very Low Very Low
beta blocker 12 5.00 Very Low Very Low Very Low
headache 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Heart Disease 272 99.00 Very High Very High Very High
Bacterial Meningitis 16 97.84 Very High Very High Very High
Pneumonia 15 95.36 Very High Very High Very High
Autoimmune Disease 10 94.52 High High
Nicotine Addiction 3 93.84 High High
Pulmonary Disease 5 88.80 High High
Infection 9 55.60 Quite High
Acute Myocarditis 52 49.60 Quite Low
Viral Infection 14 41.16 Quite Low
Disease 14 39.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The first novel finding from this study is that subcutaneous 23-PPV results in increased immunoglobulin levels in BAL. 23-PPV is protective against invasive pneumococcal disease [34] but does not protect adults against pneumonia [17], and has been shown to cause an excess of pneumonia in some studies [15].
Positive_regulation (results) of Positive_regulation (increased) of immunoglobulin associated with bacterial meningitis and pneumonia
1) Confidence 0.14 Published 2008 Journal Vaccine Section Body Doc Link PMC2612086 Disease Relevance 0.79 Pain Relevance 0
Smaller concentrations of nonmaternal fetal cells may aid the viability of the fetus, but higher levels may trigger autoimmune disease.50 Development of autoantibodies against smooth and cardiac muscle has also been reported.5,50 These autoantibodies may cross react with the myocardium and can cause cardiomyopathy.5,25,50,62 The higher rate of PPCM in twin pregnancies and its familial predisposition also support this autoimmune theory.32 Warraich et al. found markedly increased levels of immunoglobulin (IgG and subclasses) in PPCM patients.
Positive_regulation (increased) of Positive_regulation (support) of immunoglobulin in myocardium associated with autoimmune disease and coronary heart disease
2) Confidence 0.00 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628138 Disease Relevance 0.69 Pain Relevance 0
Smaller concentrations of nonmaternal fetal cells may aid the viability of the fetus, but higher levels may trigger autoimmune disease.50 Development of autoantibodies against smooth and cardiac muscle has also been reported.5,50 These autoantibodies may cross react with the myocardium and can cause cardiomyopathy.5,25,50,62 The higher rate of PPCM in twin pregnancies and its familial predisposition also support this autoimmune theory.32 Warraich et al. found markedly increased levels of immunoglobulin (IgG and subclasses) in PPCM patients.
Positive_regulation (support) of Positive_regulation (increased) of immunoglobulin in myocardium associated with autoimmune disease and coronary heart disease
3) Confidence 0.00 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628138 Disease Relevance 0.69 Pain Relevance 0

General Comments

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