INT257450

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Context Info
Confidence 0.62
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.14
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (MUC5B) cell adhesion (MUC5B)
Anatomy Link Frequency
goblet cells 1
MUC5B (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 111 78.72 Quite High
Inflammatory response 11 45.40 Quite Low
cytokine 63 30.48 Quite Low
chemokine 17 14.04 Low Low
Inflammatory mediators 24 5.00 Very Low Very Low Very Low
bradykinin 6 5.00 Very Low Very Low Very Low
metalloproteinase 5 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
potassium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Otitis Media With Effusion 92 100.00 Very High Very High Very High
Otitis Media 134 85.28 High High
Recurrence 3 81.44 Quite High
INFLAMMATION 144 78.72 Quite High
Syndrome 52 50.00 Quite Low
Adhesions 14 41.84 Quite Low
Cholesteatoma 48 5.00 Very Low Very Low Very Low
Dry Eye 28 5.00 Very Low Very Low Very Low
Sjoegrens Syndrome 26 5.00 Very Low Very Low Very Low
Infection 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both secreted (MUC2, MUC5AC, MUC5B, and MUC7) and membrane bound (MUC1, MUC4, and MUC16) mucin forms have been reported to be expressed by ocular surface epithelia [6,21,22].
Localization (secreted) of MUC5B
1) Confidence 0.62 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2613075 Disease Relevance 0 Pain Relevance 0
Smirnova et al. (104) assessed the effects of IL-8 and other proinflammatory cyokines on goblet cells using human goblet cell line HT29-MTX which secretes two OME-related mucins, MUC5AC and MUC5B.
Localization (secretes) of MUC5B in goblet cells associated with otitis media with effusion
2) Confidence 0.24 Published 2008 Journal Clinical and Experimental Otorhinolaryngology Section Body Doc Link PMC2671742 Disease Relevance 1.14 Pain Relevance 0.09

General Comments

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