INT257524

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Context Info
Confidence 0.27
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mmp9) extracellular space (Mmp9) extracellular region (Mmp9)
proteinaceous extracellular matrix (Mmp9) extracellular matrix organization (Mmp9) protein complex (Mmp9)
Mmp9 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 37 100.00 Very High Very High Very High
Central nervous system 25 80.00 Quite High
Inflammation 6 71.48 Quite High
Multiple sclerosis 12 43.88 Quite Low
Bioavailability 2 29.00 Quite Low
Spinal cord 3 11.60 Low Low
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Freund adjuvant 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Sclerosis 35 75.88 Quite High
INFLAMMATION 7 71.48 Quite High
Disease 9 34.40 Quite Low
Demyelinating Disease 1 5.60 Low Low
Immunization 5 5.00 Very Low Very Low Very Low
Autoimmune Disease 4 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 4 5.00 Very Low Very Low Very Low
Paralysis 3 5.00 Very Low Very Low Very Low
Autoimmune Hepatitis 1 5.00 Very Low Very Low Very Low
Communicable Diseases 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Specifically, the reduction of MMP-9 proteolytic activity following PEG minocycline-liposomes treatment was more substantial when cells were harvested after 6 hours than after 1 hour, both with PEG minocycline-liposome preparations containing CaCl2 or MgCl2 (Fig. 1A).
Positive_regulation (following) of Negative_regulation (reduction) of MMP-9 associated with metalloproteinase
1) Confidence 0.27 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2613526 Disease Relevance 0.15 Pain Relevance 0.36

General Comments

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