INT257590

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.44
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (DMD) extracellular space (Pth) extracellular region (Pth)
cytoskeleton (DMD) nucleus (DMD) cellular_component (Pth)
Anatomy Link Frequency
neck 1
abdomen 1
spine 1
Pth (Rattus norvegicus)
DMD (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 10 5.00 Very Low Very Low Very Low
alcohol 7 5.00 Very Low Very Low Very Low
Osteoarthritis 5 5.00 Very Low Very Low Very Low
Acute pain 4 5.00 Very Low Very Low Very Low
Bioavailability 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
anticonvulsant 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoporosis 168 80.40 Quite High
Endometriosis (extended) 11 79.88 Quite High
Hypercalcemia 57 69.84 Quite High
Frailty 32 5.00 Very Low Very Low Very Low
Disease 27 5.00 Very Low Very Low Very Low
Kidney Stones 16 5.00 Very Low Very Low Very Low
Osteoporotic Fractures 15 5.00 Very Low Very Low Very Low
Obesity 12 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 11 5.00 Very Low Very Low Very Low
Hip Fractures 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A similar conclusion was reached in men, in that alendronate impaired the effects of PTH to increase BMD at the lumbar spine and femoral neck.
PTH Positive_regulation (increase) of BMD in neck
1) Confidence 0.02 Published 2008 Journal Osteoporos Int Section Body Doc Link PMC2613968 Disease Relevance 0 Pain Relevance 0
PTH for one year followed by one year of ALN treatment significantly increased lumbar spine areal BMD by 12% (p < 0.001), compared with PTH + ALN, followed by ALN (8% and 11%), and ALN for two years (8% and 6%).
PTH Positive_regulation (increased) of BMD in spine
2) Confidence 0.01 Published 2007 Journal Clinical Interventions in Aging Section Body Doc Link PMC2684083 Disease Relevance 0.07 Pain Relevance 0
Different studies have shown that, when administered intermittently as a subcutaneous injection in the abdomen, PTH increases bone mineral density (BMD) and prevents vertebral fractures.
PTH Positive_regulation (increases) of BMD in abdomen
3) Confidence 0.01 Published 2007 Journal Clinical Interventions in Aging Section Abstract Doc Link PMC2684083 Disease Relevance 0.37 Pain Relevance 0

General Comments

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