INT257689

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Context Info
Confidence 0.37
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Gja1) Golgi apparatus (Gja1) transmembrane transport (Gja1)
cell-cell signaling (Gja1) cytoplasm (Gja1) signal transducer activity (Gja1)
Anatomy Link Frequency
myocardium 1
Gja1 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 1 95.80 Very High Very High Very High
action potential duration 20 5.00 Very Low Very Low Very Low
Action potential 10 5.00 Very Low Very Low Very Low
potassium channel 2 5.00 Very Low Very Low Very Low
sodium channel 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Calcium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Heart Disease 3 96.84 Very High Very High Very High
Cv Unclassified Under Development 2 95.80 Very High Very High Very High
Infarction 1 95.40 Very High Very High Very High
Dilated Cardiomyopathy 1 93.80 High High
Targeted Disruption 5 60.96 Quite High
Malignant Neoplastic Disease 1 51.68 Quite High
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Heart Rate Under Development 1 5.00 Very Low Very Low Very Low
Myocardial Infarction 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
downregulation of connexin43 (Cx43), the major cardiac gap junction protein subtype, has been described in cardiac disease including ischemia, infarction, hibernating myocardium, and dilated cardiomyopathy (20, 21, 24, 30).
Negative_regulation (downregulation) of connexin43 in myocardium associated with heart disease, ischemia, dilated cardiomyopathy and infarction
1) Confidence 0.37 Published 2008 Journal American Journal of Physiology - Heart and Circulatory Physiology Section Body Doc Link PMC2614590 Disease Relevance 0.58 Pain Relevance 0.05

General Comments

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