INT257797

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Context Info
Confidence 0.34
First Reported 2009
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Grap2) nucleus (Grap2) cytoplasm (Grap2)
Grap2 (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate receptor 13 100.00 Very High Very High Very High
Pyramidal cell 45 89.12 High High
nMDA receptor 72 84.88 Quite High
Hippocampus 7 5.00 Very Low Very Low Very Low
nMDA receptor antagonist 4 5.00 Very Low Very Low Very Low
ketamine 3 5.00 Very Low Very Low Very Low
gABA 2 5.00 Very Low Very Low Very Low
Action potential 2 5.00 Very Low Very Low Very Low
long-term potentiation 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Convulsion 30 72.72 Quite High
Infection 5 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low
Generalized Anxiety Disorder 2 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 2 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 2 5.00 Very Low Very Low Very Low
Epilepsy 1 5.00 Very Low Very Low Very Low
Body Weight 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because either enhanced excitation or reduced inhibition can increase the excitability of hippocampal CA3 network, we examined the mRNA levels of excitatory glutamate receptor (GluR) subunits and glutamic acid decarboxylases (GADs) expressed in the hippocampal CA3 region of the mutant mice by in situ hybridization (Fig. 7A, Table 1).
Spec (examined) Transcription (levels) of GADs associated with glutamate receptor
1) Confidence 0.34 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2615205 Disease Relevance 0.07 Pain Relevance 0.54

General Comments

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