INT257816

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.58
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 3.66
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (PAFAH1B1) cytosol (PAFAH1B1) transport (PAFAH1B1)
nuclear envelope (PAFAH1B1) nucleolus (PAFAH1B1) nucleus (PAFAH1B1)
Anatomy Link Frequency
blood 1
PAFAH1B1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 135 92.12 High High
headache 3 87.60 High High
abdominal pain 3 86.08 High High
Inflammation 3 79.36 Quite High
Disease Link Frequency Relevance Heat
Endotoxemia 3 99.18 Very High Very High Very High
Sepsis 12 99.00 Very High Very High Very High
Leptospirosis 138 94.96 High High
Hemorrhage 135 92.12 High High
Disease 48 92.04 High High
Chills 3 88.24 High High
Headache 3 87.60 High High
Myalgia 3 86.80 High High
Abdominal Pain 3 86.08 High High
Asthma 3 81.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Graham et al. reported decreased PAF-AH serum activity in blood samples from septic patients and the half-life of PAF was prolonged in the serum of dying septic patients compared to survivors or normal volunteers [38].
Negative_regulation (decreased) of PAF-AH in blood
1) Confidence 0.58 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2615213 Disease Relevance 1.33 Pain Relevance 0.18
However, in the Swiss and C57BL6 mouse models of endotoxemia administrated by LPS, serum activity of PAF-AH is significantly decreased within 24 hr after the challenge and then returns to baseline in surviving animals [30].
Negative_regulation (decreased) of PAF-AH associated with endotoxemia
2) Confidence 0.58 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2615213 Disease Relevance 0.97 Pain Relevance 0.07
Furthermore, in mouse models, serum activity of PAF-AH is significantly decreased within 24 hr after the challenge and then returns to baseline in surviving animals [30].
Negative_regulation (decreased) of PAF-AH
3) Confidence 0.58 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2615213 Disease Relevance 1.37 Pain Relevance 0.25

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox