INT257879

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Context Info
Confidence 0.28
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.54
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein complex (Eif4e, Cdkn1b) cytoplasm (Eif4e, Cdkn1b) cytosol (Cdkn1b)
cell death (Cdkn1b) RNA binding (Eif4e) nucleus (Cdkn1b)
Eif4e (Rattus norvegicus)
Cdkn1b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 3 60.04 Quite High
agonist 3 56.80 Quite High
cytokine 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cardiovascular Disease 2 91.76 High High
Hyperplasia 4 90.92 High High
Hyperglycemia 2 69.52 Quite High
Diabetes Mellitus 7 68.80 Quite High
INFLAMMATION 3 60.04 Quite High
Insulin Resistance 2 54.80 Quite High
Injury 16 5.00 Very Low Very Low Very Low
Neointima 11 5.00 Very Low Very Low Very Low
Retinoblastoma 2 5.00 Very Low Very Low Very Low
Starvation 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
By inactivating P70S6K and eIF4E, rapamycin increases the activity of p27Kip1 and RB, subsequently resulting in inhibition of VSMC proliferation.
Negative_regulation (inactivating) of eIF4E Positive_regulation (increases) of p27Kip1
1) Confidence 0.28 Published 2008 Journal Yonsei Medical Journal Section Body Doc Link PMC2615285 Disease Relevance 0.54 Pain Relevance 0.06

General Comments

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