INT257896

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Sostdc1) extracellular region (Sostdc1) plasma membrane (GRIN1)
Sostdc1 (Rattus norvegicus)
GRIN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
nMDA receptor 30 100.00 Very High Very High Very High
Nicotine 139 99.60 Very High Very High Very High
cocaine 11 97.74 Very High Very High Very High
nMDA receptor antagonist 18 84.64 Quite High
Glutamate 25 52.12 Quite High
tolerance 39 50.00 Quite Low
addiction 34 50.00 Quite Low
antagonist 19 50.00 Quite Low
Morphine 3 37.92 Quite Low
Glutamate receptor 6 32.00 Quite Low
Disease Link Frequency Relevance Heat
Attention Deficit Hyperactivity Disorder 1 87.44 High High
Drug Dependence 20 50.00 Quite Low
Nicotine Addiction 19 5.00 Very Low Very Low Very Low
Opiate Addiction 6 5.00 Very Low Very Low Very Low
Syndrome 6 5.00 Very Low Very Low Very Low
Recurrence 4 5.00 Very Low Very Low Very Low
Tremor 3 5.00 Very Low Very Low Very Low
Sleep Disorders 2 5.00 Very Low Very Low Very Low
Ocular Toxicity (including Many Sub-types) 2 5.00 Very Low Very Low Very Low
Cocaine Dependence 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results are consistent with previous data demonstrating that pretreatment with MK-801 blocks the development of sensitization to drugs of abuse including nicotine, cocaine, amphetamine or methamphetamine.94 Furthermore, these results also demonstrate that nicotine-induced behavioral sensitization requires the activation of NMDA receptors not only for its development, but also for its expression.
sensitization Positive_regulation (requires) of Positive_regulation (activation) of NMDA associated with nmda receptor, nicotine and cocaine
1) Confidence 0.00 Published 2008 Journal Yonsei Medical Journal Section Body Doc Link PMC2615322 Disease Relevance 0.09 Pain Relevance 0.83

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox