INT257933

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.14
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (H2-Ab1) plasma membrane (H2-Ab1) intracellular (H2-Ab1)
transcription factor binding (H2-Ab1)
Anatomy Link Frequency
macrophages 2
H2-Ab1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 36 83.04 Quite High
cytokine 24 80.16 Quite High
Inflammatory response 14 33.68 Quite Low
cINOD 9 5.00 Very Low Very Low Very Low
Abeta 1 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
transdermal 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 53 83.04 Quite High
Alzheimer's Dementia 5 53.20 Quite High
Anaerobic Bacterial Infections 1 22.08 Low Low
Infection 4 21.84 Low Low
Aging 14 15.52 Low Low
Foreign Bodies 1 12.24 Low Low
Disease 118 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 10 5.00 Very Low Very Low Very Low
Targeted Disruption 10 5.00 Very Low Very Low Very Low
Immunization 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-mediated induction of the MHC II gene (H2-Ab1) is impaired in macrophages from aged mice due to the decreased binding of transcription factors to the promoter [64].
Negative_regulation (impaired) of Positive_regulation (induction) of H2-Ab1 in macrophages
1) Confidence 0.05 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2615427 Disease Relevance 0.14 Pain Relevance 0.08

General Comments

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