INT257992

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PTGER2, GOPC) Golgi apparatus (GOPC) cytoplasm (GOPC)
signal transducer activity (PTGER2)
Anatomy Link Frequency
HT-29 1
PTGER2 (Homo sapiens)
GOPC (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 26 50.72 Quite High
Potency 4 43.80 Quite Low
withdrawal 7 5.00 Very Low Very Low Very Low
cINOD 7 5.00 Very Low Very Low Very Low
antagonist 7 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 64 50.00 Quite Low
Apoptosis 17 12.96 Low Low
Bordatella Infection 4 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Adenocarcinoma 1 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We suspect that a drop in cAMP levels, as reflected by a marked reduction in PKA substrate phosphorylation e.g. by 1 or 100 nM PGE2 in HT-29 cells (Fig. 3C) did largely pass undetected in the cAMP measurements.
PGE2 Negative_regulation (reduction) of Fig in HT-29
1) Confidence 0.04 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2615781 Disease Relevance 0 Pain Relevance 0.03

General Comments

This test has worked.

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