INT258010

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Context Info
Confidence 0.69
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.51
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Rassf1) plasma membrane (Rassf1) cytoskeleton (Rassf1)
nucleus (Rassf1) cell cycle (Rassf1) cytoplasm (Rassf1)
Anatomy Link Frequency
MCF-7 1
Rassf1 (Mus musculus)
Pain Link Frequency Relevance Heat
local anesthetic 11 55.20 Quite High
depression 3 44.20 Quite Low
Central nervous system 1 38.12 Quite Low
Bioavailability 9 30.24 Quite Low
Neurotransmitter 1 9.12 Low Low
gABA 5 7.76 Low Low
antagonist 37 5.00 Very Low Very Low Very Low
Inflammation 11 5.00 Very Low Very Low Very Low
agonist 9 5.00 Very Low Very Low Very Low
Angina 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nasopharynx Cancer 1 99.64 Very High Very High Very High
Breast Cancer 17 95.32 Very High Very High Very High
Cancer 131 83.00 Quite High
Renal Disease 4 58.12 Quite High
Coma 1 44.60 Quite Low
Depression 3 44.20 Quite Low
Convulsion 1 43.24 Quite Low
Tremor 2 42.16 Quite Low
Akathisia 1 41.80 Quite Low
Heart Rate Under Development 18 35.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Procaine has also shown to inhibit growth and to reactivate the expression of RASSF1A mRNA in nasopharyngeal cancer cell lines [191], as well as to reactivate estrogen receptor-gene expression in MCF-7 breast cancer cells [192].
Transcription (expression) of RASSF1A in MCF-7 associated with nasopharynx cancer and breast cancer
1) Confidence 0.69 Published 2008 Journal Mol Cancer Section Body Doc Link PMC2615789 Disease Relevance 0.51 Pain Relevance 0.06

General Comments

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