INT258018

Context Info Confidence 0.00 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 1.59 Pain Relevance 0.10

cell differentiation (RASGRP1) small molecule metabolic process (AGT) aging (AGT) Golgi apparatus (RASGRP1) endoplasmic reticulum (RASGRP1) extracellular matrix organization (AGT)

Anatomy Link Frequency blood 1 AGT (Homo sapiens) RASGRP1 (Homo sapiens)

Pain Link Frequency Relevance Heat antagonist 74 99.12 cINOD 2 46.04 Inflammation 22 5.00 local anesthetic 22 5.00 Bioavailability 18 5.00 agonist 18 5.00 Angina 14 5.00 gABA 10 5.00 Calcium channel 8 5.00 fibrosis 8 5.00

Disease Link Frequency Relevance Heat Lung Cancer 16 96.72 Heart Rate Under Development 36 92.52 Pressure Volume 2 Under Development 2 91.48 Hypertension 18 90.96 Pressure And Volume Under Development 12 84.80 Glioblastoma 6 78.24 Cancer 262 73.24 Colon Cancer 8 72.96 Pathologic Constriction 2 70.28 Renal Artery Obstruction 2 69.48

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Angiotensin II (AngII), the biologically active peptide of the renin-angiotensin system (RAS), is a major blood pressure and cardiovascular homeostasis regulator and is also recognized as a potent mitogen.

Angiotensin II Binding (recognized) of RAS in blood

1) Confidence 0.00 Published 2008 Journal Mol Cancer Section Body Doc Link PMC2615789 Disease Relevance 0.59 Pain Relevance 0.05

Angiotensin II (AngII), the biologically active peptide of the renin-angiotensin system (RAS), is also recognized as a potent mitogen that participates in various pathological situations involving tissue remodeling.

Angiotensin II Binding (recognized) of RAS

2) Confidence 0.00 Published 2008 Journal Mol Cancer Section Body Doc Link PMC2615789 Disease Relevance 1.00 Pain Relevance 0.05

General Comments

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