INT258045

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Context Info
Confidence 0.36
First Reported 2008
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.78
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (BCL2) cell morphogenesis (BCL2) endoplasmic reticulum (BCL2)
intracellular (BCL2) cytoplasm (BCL2) cytosol (BCL2)
BCL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
corticosteroid 1 50.24 Quite High
antagonist 37 41.92 Quite Low
Bile 2 24.36 Low Low
dexamethasone 2 17.68 Low Low
Inflammation 11 5.00 Very Low Very Low Very Low
local anesthetic 11 5.00 Very Low Very Low Very Low
Bioavailability 9 5.00 Very Low Very Low Very Low
agonist 9 5.00 Very Low Very Low Very Low
Angina 7 5.00 Very Low Very Low Very Low
gABA 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 96 100.00 Very High Very High Very High
Prostate Cancer 11 100.00 Very High Very High Very High
Adenocarcinoma 2 98.36 Very High Very High Very High
Lung Cancer 10 96.04 Very High Very High Very High
Ovarian Cancer 7 92.32 High High
Repression 4 72.64 Quite High
Neuroblastoma 3 62.84 Quite High
Cancer 154 55.84 Quite High
Breast Cancer 18 55.20 Quite High
Death 14 51.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, no significant changes in BCL2 protein levels were detected at 0, 24, or 72 h in the empty vector-transfected cells with or without miR-34a inhibition (Figure 9B, bottom panel).
Neg (no) Positive_regulation (changes) of Neg (no) Regulation (changes) of BCL2
1) Confidence 0.36 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2883962 Disease Relevance 0.66 Pain Relevance 0
Mifepristone also induced apoptosis in human prostate cancer LNCaP cells by regulating Bcl-2 gene and TGF?
Positive_regulation (induced) of Regulation (regulating) of Bcl-2 gene associated with prostate cancer and apoptosis
2) Confidence 0.10 Published 2008 Journal Mol Cancer Section Body Doc Link PMC2615789 Disease Relevance 1.12 Pain Relevance 0.03

General Comments

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