INT258058

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Context Info
Confidence 0.08
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.89
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (TGFB2) extracellular space (TGFB2) cell death (TGFB2)
extracellular region (TGFB2) cell morphogenesis (TGFB2) embryo development (TGFB2)
TGFB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
withdrawal 2 75.80 Quite High
carbamazepine 2 48.96 Quite Low
antagonist 37 5.00 Very Low Very Low Very Low
Inflammation 11 5.00 Very Low Very Low Very Low
local anesthetic 11 5.00 Very Low Very Low Very Low
Bioavailability 9 5.00 Very Low Very Low Very Low
agonist 9 5.00 Very Low Very Low Very Low
Angina 7 5.00 Very Low Very Low Very Low
gABA 5 5.00 Very Low Very Low Very Low
Calcium channel 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 36 100.00 Very High Very High Very High
Adhesions 3 100.00 Very High Very High Very High
Cancer 131 96.90 Very High Very High Very High
Aging 1 84.64 Quite High
Metastasis 5 83.32 Quite High
Solid Tumor 2 70.00 Quite High
Malignant Neoplastic Disease 10 68.64 Quite High
Hematological Disease 1 67.84 Quite High
Breast Cancer 17 58.24 Quite High
Leukemia 3 46.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, whole genome expression by microarray analysis from primary tumors of VPA-treated patients demonstrate significant up-regulation of hundreds of genes belonging to multiple pathways including ribosomal proteins, oxidative phosphorylation, MAPK signaling, focal adhesion, cell cycle, antigen processing and presentation, proteasome, apoptosis, PI3K, Wnt signaling, calcium signaling, TGF-beta signaling, and ubiquitin-mediated proteolysis, among others [175].
Phosphorylation (phosphorylation) of TGF-beta associated with cancer, apoptosis and adhesions
1) Confidence 0.08 Published 2008 Journal Mol Cancer Section Body Doc Link PMC2615789 Disease Relevance 0.89 Pain Relevance 0.04

General Comments

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