INT258071

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.19
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (APRT) small molecule metabolic process (APRT) transferase activity, transferring glycosyl groups (APRT)
nucleolus (APRT) nucleus (APRT) cytoplasm (APRT)
APRT (Homo sapiens)
Pain Link Frequency Relevance Heat
ischemia 1 99.56 Very High Very High Very High
abdominal pain 2 59.16 Quite High
tolerance 3 35.00 Quite Low
Bioavailability 9 13.64 Low Low
antagonist 37 5.00 Very Low Very Low Very Low
Inflammation 11 5.00 Very Low Very Low Very Low
local anesthetic 11 5.00 Very Low Very Low Very Low
agonist 9 5.00 Very Low Very Low Very Low
Angina 7 5.00 Very Low Very Low Very Low
gABA 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 7 99.92 Very High Very High Very High
Cv Unclassified Under Development 1 99.56 Very High Very High Very High
Shock 3 98.80 Very High Very High Very High
Cancer 131 87.08 High High
Diabetes Mellitus 7 85.96 High High
Gastrointestinal Neoplasms 1 76.84 Quite High
Polyps 2 73.68 Quite High
Syndrome 4 68.52 Quite High
Hepatotoxicity 2 63.72 Quite High
Lactic Acidosis 1 61.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
AMPK is activated under conditions that deplete cellular ATP and elevate AMP levels such as glucose deprivation, hypoxia, ischemia, and heat shock, which are associated with an increased AMP/ATP ratio [268].
Positive_regulation (elevate) of Negative_regulation (deprivation) of AMP associated with hypoxia, ischemia and shock
1) Confidence 0.02 Published 2008 Journal Mol Cancer Section Body Doc Link PMC2615789 Disease Relevance 1.19 Pain Relevance 0.11

General Comments

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