INT258080

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.44
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ABCC3) small molecule metabolic process (ABCC3) ATPase activity (ABCC3)
plasma membrane (ABCC3) transmembrane transport (ABCC3)
ABCC3 (Homo sapiens)
Pain Link Frequency Relevance Heat
adenocard 2 99.24 Very High Very High Very High
antagonist 37 98.68 Very High Very High Very High
Kinase C 3 93.08 High High
Calcium channel 4 84.08 Quite High
vincristine 1 34.00 Quite Low
Angina 7 17.28 Low Low
Inflammation 11 5.00 Very Low Very Low Very Low
local anesthetic 11 5.00 Very Low Very Low Very Low
Bioavailability 9 5.00 Very Low Very Low Very Low
agonist 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 131 85.92 High High
Hyperplasia 2 74.32 Quite High
Apoptosis 36 72.88 Quite High
Breast Cancer 17 71.92 Quite High
Lung Cancer 8 43.68 Quite Low
Hypertension 9 18.24 Low Low
Cv General 3 Under Development 7 17.28 Low Low
Increased Venous Pressure Under Development 6 9.16 Low Low
Heart Rate Under Development 18 5.00 Very Low Very Low Very Low
Disease 18 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CCA also increase cytotoxicity when added to chemotherapy, an effect attributed to blocking the multidrug resistance protein P-glycoprotein, which acts as an adenosine triphosphate-dependent drug efflux pump, reducing intracellular chemotherapeutic drug accumulation [29].
Positive_regulation (attributed) of Negative_regulation (blocking) of multidrug resistance protein P-glycoprotein associated with adenocard and antagonist
1) Confidence 0.06 Published 2008 Journal Mol Cancer Section Body Doc Link PMC2615789 Disease Relevance 0.44 Pain Relevance 0.31

General Comments

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