INT258151

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Context Info
Confidence 0.28
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IGFBP3) extracellular region (IGFBP3) endoplasmic reticulum (Hcrt)
nucleus (IGFBP3) cytoplasm (Hcrt)
Anatomy Link Frequency
neural 2
IGFBP3 (Homo sapiens)
Hcrt (Mus musculus)
Pain Link Frequency Relevance Heat
Locus ceruleus 8 5.00 Very Low Very Low Very Low
Neuropeptide 3 5.00 Very Low Very Low Very Low
Dopamine 2 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
cocaine 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
nMDA receptor 1 5.00 Very Low Very Low Very Low
Dynorphin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 43 91.60 High High
Sleep Disorders 69 86.84 High High
Death 10 57.80 Quite High
Neuroblastoma 2 56.08 Quite High
Disease 4 6.96 Low Low
Sprains And Strains 5 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Hypersensitivity 3 5.00 Very Low Very Low Very Low
Hypoxia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IGFBP3 reduces promotor activity of hypocretin in neural cell lines
IGFBP3 Negative_regulation (reduces) of hypocretin Binding (activity) of in neural
1) Confidence 0.28 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2617764 Disease Relevance 0.49 Pain Relevance 0

General Comments

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