INT258173

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.44
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Cpox) oxidoreductase activity (Cpox) RNA binding (Gtf3a)
nucleus (Gtf3a) intracellular (Gtf3a) DNA binding (Gtf3a)
Anatomy Link Frequency
lung 3
Cpox (Mus musculus)
Gtf3a (Mus musculus)
Pain Link Frequency Relevance Heat
COX-2 inhibitor 7 81.84 Quite High
cINOD 8 62.36 Quite High
Inflammation 2 54.92 Quite High
palliative 1 45.12 Quite Low
aspirin 1 35.84 Quite Low
IPN 1 29.36 Quite Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 7 99.40 Very High Very High Very High
Cancer 73 98.88 Very High Very High Very High
Colorectal Cancer 1 96.92 Very High Very High Very High
Metastasis 20 95.88 Very High Very High Very High
Lewis Lung Carcinoma 14 86.32 High High
Colon Cancer 3 81.60 Quite High
Toxicity 4 77.04 Quite High
INFLAMMATION 3 54.92 Quite High
Solid Tumor 1 47.00 Quite Low
Adenoma 1 42.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Connolly et al. proposed that in vitro COX inhibitors decreased vascular endothelial growth factor production and increased apoptosis of tumor cells, as well as a reduced primary tumor weight, the number of lung metastases, and microvessel density in primary tumors in mice [28].
Negative_regulation (inhibitors) of COX in lung Negative_regulation (decreased) of Gene_expression (production) of factor in lung associated with cancer, apoptosis and metastasis
1) Confidence 0.00 Published 2008 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2621123 Disease Relevance 1.44 Pain Relevance 0.33

General Comments

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