INT258202

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Context Info
Confidence 0.14
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.20
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ROCK1, MYL2) cytoskeleton (ROCK1, MYL2) signal transduction (ROCK1)
Golgi apparatus (ROCK1) cytoplasm (ROCK1)
Anatomy Link Frequency
growth cone 1
ROCK1 (Homo sapiens)
MYL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 11 5.00 Very Low Very Low Very Low
Dopamine 3 5.00 Very Low Very Low Very Low
dopamine receptor 2 5.00 Very Low Very Low Very Low
Clonidine 2 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Hippocampus 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 1 100.00 Very High Very High Very High
Shock 2 96.44 Very High Very High Very High
Cancer 3 8.92 Low Low
Apoptosis 4 5.80 Low Low
Bordatella Infection 5 5.00 Very Low Very Low Very Low
Exencephaly /

Neural Tube Defects

3 5.00 Very Low Very Low Very Low
Wound Healing 2 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low
Spinal Injuries 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Specifically, p160 ROCK increases actin contractility and stress fiber formation via myosin-II regulatory light chain (MLC) [41] and decreases actin depolymerization via LIM kinases to regulate growth cone collapse [24].
ROCK Positive_regulation (increases) of myosin-II regulatory light chain in growth cone associated with stress and shock
1) Confidence 0.14 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2621239 Disease Relevance 0.20 Pain Relevance 0

General Comments

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