INT258279

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Context Info
Confidence 0.45
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.26
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Hmgb1) extracellular region (Hmgb1) cell morphogenesis (Hmgb1)
nucleolus (Hmgb1) chromosome (Hmgb1) nucleus (Hmgb1)
Hmgb1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 10 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 205 95.24 Very High Very High Very High
Brain Tumor 47 50.00 Quite Low
Glioblastoma 30 5.00 Very Low Very Low Very Low
Glioma 23 5.00 Very Low Very Low Very Low
INFLAMMATION 9 5.00 Very Low Very Low Very Low
Melanoma 8 5.00 Very Low Very Low Very Low
Apoptosis 8 5.00 Very Low Very Low Very Low
Death 7 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Immunotherapy Of Cancer 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HMGB1-depleting immunoglobulins (custom antibody generated by New England Peptides) or rabbit IgG isotype control immunoglobulins (Sigma) were affinity purified (Montage, Millipore), tested for LPS contamination (Lonza), and injected in mice on day 19, 22, and 27 after tumor cell implantation (600 ?
Positive_regulation (generated) of HMGB1 Binding (affinity) of associated with cancer
1) Confidence 0.45 Published 2009 Journal PLoS Medicine Section Body Doc Link PMC2621261 Disease Relevance 0.26 Pain Relevance 0

General Comments

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