INT258399

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL6R, IL6ST) extracellular region (IL6R, IL6ST) plasma membrane (IL6R, IL6ST)
enzyme binding (IL6R)
IL6R (Homo sapiens)
IL6ST (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 45 84.48 Quite High
Inflammation 11 81.92 Quite High
methotrexate 24 71.44 Quite High
chemokine 1 21.40 Low Low
Arthritis 6 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
abatacept 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Leflunomide 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 46 84.48 Quite High
INFLAMMATION 11 81.92 Quite High
Disease 24 76.52 Quite High
Fatigue 6 59.20 Quite High
Weight Loss 1 58.84 Quite High
Fever 1 58.32 Quite High
Hypergammaglobulinemia 1 38.80 Quite Low
Thrombosis Related Under Development 1 32.20 Quite Low
Chronic Disease 2 28.92 Quite Low
Anaemia 1 28.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, in order to transduce a signal, the combination of IL-6/IL-6R must also bind a ubiquitous transmembrane protein, glycoprotein (gp) 130 (CD130).
IL-6R Binding (bind) of CD130
1) Confidence 0.06 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2621374 Disease Relevance 0.61 Pain Relevance 0.18

General Comments

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