INT258408

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Context Info
Confidence 0.26
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (ACR) DNA binding (ACR) protein complex (ACR)
ACR (Homo sapiens)
Pain Link Frequency Relevance Heat
methotrexate 24 99.44 Very High Very High Very High
rheumatoid arthritis 45 67.20 Quite High
Inflammation 11 5.00 Very Low Very Low Very Low
Arthritis 6 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
abatacept 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Leflunomide 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 46 67.20 Quite High
Disease 24 12.96 Low Low
INFLAMMATION 11 5.00 Very Low Very Low Very Low
Infection 9 5.00 Very Low Very Low Very Low
Disorder Of Lipid Metabolism 9 5.00 Very Low Very Low Very Low
Fatigue 6 5.00 Very Low Very Low Very Low
Juvenile Chronic Polyarthritis 3 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 2 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Additionally, those patients receiving 4 mg/kg or 8 mg/kg of tocilizumab in combination with MTX also achieved an ACR50 and ACR70 response that was significantly increased in comparison with MTX alone.
Positive_regulation (increased) of Regulation (response) of ACR70 associated with methotrexate
1) Confidence 0.26 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2621374 Disease Relevance 0.07 Pain Relevance 0.36

General Comments

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