INT258522

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.05
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (DDR1, RET) endosome (RET) signal transduction (RET)
extracellular region (DDR1) cell adhesion (DDR1)
DDR1 (Homo sapiens)
RET (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 4 78.88 Quite High
metalloproteinase 4 52.16 Quite High
Sicca syndrome 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Thyroid Neoplasm 161 100.00 Very High Very High Very High
Multiple Endocrine Neoplasia Type 2a 1 98.96 Very High Very High Very High
Cancer 54 96.80 Very High Very High Very High
Multiple Endocrine Neoplasia 4 85.48 High High
Hereditary Neoplastic Syndromes 1 43.16 Quite Low
Multiple Endocrine Neoplasia Type 2b 1 34.16 Quite Low
Chromosome Inversion 1 32.40 Quite Low
Carcinoma 23 12.24 Low Low
Disease 24 5.00 Very Low Very Low Very Low
Metastasis 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The cumulative result of the point mutations associated with MEN 2A and 2B and FMTC and the chromosomal rearrangements associated with PTC is activation of the RET receptor tyrosine kinase (RTK).
RTK Binding (associated) of PTC associated with multiple endocrine neoplasia type 2a and thyroid neoplasm
1) Confidence 0.03 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2621417 Disease Relevance 1.05 Pain Relevance 0.10

General Comments

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