INT258564

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Context Info
Confidence 0.27
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.67
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (NOTCH1, Crlf2) plasma membrane (NOTCH1, Crlf2) cytosol (NOTCH1)
nucleoplasm (NOTCH1) Golgi apparatus (NOTCH1) nucleus (NOTCH1)
Anatomy Link Frequency
Notch 1
NOTCH1 (Homo sapiens)
Crlf2 (Mus musculus)
Pain Link Frequency Relevance Heat
palliative 4 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
Sicca syndrome 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Thyroid Neoplasm 161 91.68 High High
Manic Depressive Disorder 1 81.84 Quite High
Cancer 54 66.64 Quite High
Pancreatic Cancer 1 53.68 Quite High
Colon Cancer 1 52.16 Quite High
Cervical Cancer 1 49.20 Quite Low
Renal Cancer 1 47.84 Quite Low
Lymphatic System Cancer 1 45.12 Quite Low
Apoptosis 3 35.84 Quite Low
Reprotox - General 1 1 28.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Binding of any one of the Notch ligands (Delta1 (DLL-1) or Jagged1 (JAG-1), for example) promotes a sequence of proteolytic cleavages resulting in the activated Notch intracellular domain (NICD).
Notch Binding (ligands) of Delta1 in Notch
1) Confidence 0.27 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2621417 Disease Relevance 0.67 Pain Relevance 0

General Comments

This test has worked.

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