INT258565

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Context Info
Confidence 0.39
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.89
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (EGFR) cell morphogenesis (EGFR) Golgi apparatus (EGFR)
endoplasmic reticulum (EGFR) intracellular (EGFR) enzyme binding (EGFR)
Anatomy Link Frequency
thyroid 1
EGFR (Homo sapiens)
Meta (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 4 100.00 Very High Very High Very High
palliative 4 62.20 Quite High
Glutamate 1 52.32 Quite High
Sicca syndrome 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Thyroid Neoplasm 161 99.12 Very High Very High Very High
Cancer 54 91.12 High High
Carcinoma 23 86.88 High High
Non-small-cell Lung Cancer 1 55.28 Quite High
Small Cell Lung Cancer 2 55.00 Quite High
Metastasis 15 48.48 Quite Low
Malignant Neoplastic Disease 4 33.96 Quite Low
Apoptosis 3 17.12 Low Low
Disease 24 5.00 Very Low Very Low Very Low
Recurrence 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
More recently, studies have demonstrated that differentiated thyroid cancer cell invasion in vivo is regulated through EGFR-dependent activation of matrix metalloproteinase (MMP)-2/gelatinase A (Yeh et al 2006).
EGFR Positive_regulation (activation) of meta in thyroid associated with thyroid neoplasm and metalloproteinase
1) Confidence 0.39 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2621417 Disease Relevance 0.89 Pain Relevance 0.23

General Comments

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