INT258574

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Cysltr1, Cnr1) plasma membrane (Cysltr1, Cnr1) signal transducer activity (Cysltr1, Cnr1)
aging (Cnr1)
Anatomy Link Frequency
brain 2
Cysltr1 (Mus musculus)
Cnr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Endocannabinoid 25 98.12 Very High Very High Very High
Dopamine 13 84.64 Quite High
cocaine 4 59.80 Quite High
Nucleus accumbens 1 45.28 Quite Low
Ventral tegmentum 1 42.64 Quite Low
Substantia nigra 2 37.48 Quite Low
Cannabinoid receptor 1 24.40 Low Low
addiction 4 18.96 Low Low
depression 6 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 1 65.84 Quite High
Depression 6 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low
Cognitive Disorder 2 5.00 Very Low Very Low Very Low
Obsessive-compulsive Disorder 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Food Poisoning 1 5.00 Very Low Very Low Very Low
Recurrence 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, striatal LTD was found to depend on CB1 receptor activation, the primary molecular target in the brain of endocannabinoids (Gerdeman and Lovinger, 2001; Gerdeman et al., 2002).
LTD Positive_regulation (depend) of Positive_regulation (activation) of CB1 in brain associated with endocannabinoid
1) Confidence 0.01 Published 2008 Journal Frontiers in Neuroscience Section Body Doc Link PMC2622741 Disease Relevance 0.07 Pain Relevance 0.32

General Comments

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