INT258630

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Context Info
Confidence 0.24
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.20
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (IL15) aging (IL15) Golgi apparatus (IL15)
cell-cell signaling (IL15) cytoplasm (IL15) extracellular space (IL15)
Anatomy Link Frequency
joint 1
IL15 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 57 100.00 Very High Very High Very High
rheumatoid arthritis 3 99.74 Very High Very High Very High
Inflammation 14 98.76 Very High Very High Very High
Inflammatory response 4 95.16 Very High Very High Very High
corticosteroid 4 60.40 Quite High
chemokine 32 48.60 Quite Low
dexamethasone 1 43.92 Quite Low
Central nervous system 4 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 3 99.74 Very High Very High Very High
Arthritis 5 99.00 Very High Very High Very High
INFLAMMATION 18 94.76 High High
Arthralgia 10 93.80 High High
Infection 40 91.00 High High
Critical Illness 37 88.24 High High
Cancer 106 86.96 High High
Disease 58 84.04 Quite High
Influenza Virus Infection 15 83.72 Quite High
Glioma 50 80.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Among Spanish patients, serum IL15, IL12p70 and IL6 were recognized as the hallmark of severity [10].
IL15 Binding (recognized) of
1) Confidence 0.24 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2948498 Disease Relevance 1.08 Pain Relevance 0.35
Lymphodepletion could act by eliminating competition for homeostatic cytokines, in particular IL15, for which high levels can be detected only after treatment.
IL15 Binding (competition) of associated with cytokine
2) Confidence 0.11 Published 2010 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2952949 Disease Relevance 0.31 Pain Relevance 0.08
IL-7 is known to have an important role in the development of rheumatoid arthritis [39], while IL-15 has been associated with the development of joint inflammation [40].
IL-15 Binding (associated) of in joint associated with inflammation, rheumatoid arthritis and arthritis
3) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2625438 Disease Relevance 0.81 Pain Relevance 0.22

General Comments

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