INT258637

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Context Info
Confidence 0.62
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.77
Pain Relevance 2.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GCH1) small molecule metabolic process (GCH1) nucleolus (GCH1)
nucleus (GCH1) protein complex assembly (GCH1) protein complex (GCH1)
GCH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
GCH1 24 100.00 Very High Very High Very High
Neuropathic pain 5 99.64 Very High Very High Very High
Pain 106 99.54 Very High Very High Very High
Chronic pancreatitis 34 97.48 Very High Very High Very High
Visceral pain 7 92.28 High High
tolerance 1 76.32 Quite High
Pain score 1 76.24 Quite High
Catechol-O-methyltransferase 4 72.12 Quite High
Lasting pain 1 62.36 Quite High
Sciatica 3 48.28 Quite Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 7 99.64 Very High Very High Very High
Pain 109 99.54 Very High Very High Very High
Pancreatitis 63 97.76 Very High Very High Very High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

7 92.28 High High
Nerve Root Compression 3 48.28 Quite Low
Dermatitis 1 22.32 Low Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
Diabetes Mellitus 1 5.00 Very Low Very Low Very Low
Syndrome 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The initial published report of GCH1 genotypes influencing clinical pain suggested that pain pathways sensitive to changes in GCH1 expression involve neuropathic pain [7], which may be uncommon in RAP or CP.
Regulation (changes) of Gene_expression (expression) of GCH1 associated with pain, pancreatitis, neuropathic pain, gch1 and chronic pancreatitis
1) Confidence 0.62 Published 2008 Journal Mol Pain Section Body Doc Link PMC2626574 Disease Relevance 1.59 Pain Relevance 2.02

General Comments

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