INT258812

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.26
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Ace) peptidase activity (Ace) extracellular space (Ace)
extracellular region (Ace) plasma membrane (Ace)
Sugt1 (Rattus norvegicus)
Ace (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuropeptide 1 99.44 Very High Very High Very High
substance P 8 67.00 Quite High
Dopamine 2 52.84 Quite High
Ventral tegmentum 1 10.04 Low Low
Substantia nigra 2 8.48 Low Low
bradykinin 3 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Eae 1 5.00 Very Low Very Low Very Low
Opioid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 1 99.44 Very High Very High Very High
Disease 73 95.28 Very High Very High Very High
Hypokinesia 4 5.00 Very Low Very Low Very Low
Parkinsonian Disorders 4 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 4 5.00 Very Low Very Low Very Low
Tremor 3 5.00 Very Low Very Low Very Low
Syndrome 2 5.00 Very Low Very Low Very Low
Neurological Disease 1 5.00 Very Low Very Low Very Low
Coronary Artery Disease 1 5.00 Very Low Very Low Very Low
Dementia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Based on evidence linking the DD ACE genotype to longevity [34] they suggested that D allele may confer some long-term protective effect as a result of ACE' s action on neuropeptides and neuroendocrine function.
allele Positive_regulation (result) of ACE associated with aging and neuropeptide
1) Confidence 0.05 Published 2008 Journal The Open Neurology Journal Section Body Doc Link PMC2627518 Disease Relevance 1.26 Pain Relevance 0.16

General Comments

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