INT258917

Context Info Confidence 0.48 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.18 Pain Relevance 0.09

plasma membrane (HLA-H)

HLA-H (Homo sapiens)

Pain Link Frequency Relevance Heat rheumatoid arthritis 1 64.24 spinal inflammation 1 58.04 cva 2 5.00 cytokine 1 5.00

Disease Link Frequency Relevance Heat Iron Overload 6 100.00 Disease 15 94.64 Diabetes Mellitus 1 71.36 Rheumatoid Arthritis 1 64.24 Autoimmune Disease 1 63.36 Celiac Disease 1 59.36 Low Back Pain 1 58.04 Sleep Disorders 1 55.76 General Immunology 1 50.00 Neonatal Alloimmune Thrombocytopenia 4 32.84

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Then nonclassical class I-like HLA-H, also namely HFE, was identified as a hemochromatosis gene.75 HFE is located approximately 5 megabases telomeric to the HLA-A locus.

Localization (located) of HLA-H associated with iron overload

1) Confidence 0.48 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628004 Disease Relevance 1.18 Pain Relevance 0.09

General Comments

This test has worked.