INT258932

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Context Info
Confidence 0.39
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.73
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (TBX1) nucleus (TBX1) DNA binding (TBX1)
Anatomy Link Frequency
lateral 1
band 1
TBX1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 27 97.72 Very High Very High Very High
Analgesic 3 94.68 High High
Pain refractory 1 94.40 High High
depression 1 79.72 Quite High
imagery 17 68.96 Quite High
spinal stenosis 1 41.52 Quite Low
Spinal cord 2 21.12 Low Low
Perioperative pain 2 9.84 Low Low
visual analogue scale 17 5.00 Very Low Very Low Very Low
backache 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Compression Fractures 115 100.00 Very High Very High Very High
Aseptic Necrosis Of Bone 1 97.26 Very High Very High Very High
Injury 3 96.70 Very High Very High Very High
Metastasis 2 96.08 Very High Very High Very High
Hemangioma 1 95.68 Very High Very High Very High
Osteoporosis 17 95.22 Very High Very High Very High
Kyphosis 3 95.12 Very High Very High Very High
Intractable Pain 2 94.40 High High
Pain 23 92.34 High High
Osteoporotic Fractures 4 85.24 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Management of painful osteoporotic or posttraumatic VCFs.Intractable, focal band-like radicular pain that is worse with weight bearing and is relieved with rest or in a recumbent position.Pain refractory to analgesics and narcotics.Osteoporosis, aggressive hemangioma, metastatic disease, osteogenic imperfecta, trauma, or vertebral osteonecrosis resulting in a painful compression fracture.For the management of chronic nonunion following traumatic vertebral body fracturesInternal stabilization of unstable posttraumatic VCFs.Management of multiple compression fractures in a patient with poor pulmonary reserve.
Positive_regulation (stabilization) of VCFs in band associated with compression fractures, pain, pain refractory, hemangioma, analgesic, osteoporosis, metastasis, aseptic necrosis of bone and injury
1) Confidence 0.39 Published 2007 Journal Curr Rev Musculoskelet Med Section Body Doc Link PMC2684215 Disease Relevance 1.50 Pain Relevance 0.54
The procedure is minimally invasive and can improve vertebral height and stabilize osteoporotic VCFs.7-12
Positive_regulation (stabilize) of VCFs.7-12 associated with compression fractures
2) Confidence 0.22 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628047 Disease Relevance 0.75 Pain Relevance 0.11
However, we had observed that the VH of severely collapsed VCFs increased on supine lateral radiographs (SuLR) compared with standing lateral radiographs (StLR).
Positive_regulation (increased) of VCFs in lateral
3) Confidence 0.02 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2918541 Disease Relevance 0.48 Pain Relevance 0.17

General Comments

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