INT258948

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Context Info
Confidence 0.27
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 5.05
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (OFD1) mitosis (OFD1) nucleus (OFD1)
cilium (OFD1) cytoplasm (OFD1)
OFD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 2 23.84 Low Low
Disease Link Frequency Relevance Heat
Cleidocranial Dysplasia 196 100.00 Very High Very High Very High
Adamantinoma 160 99.80 Very High Very High Very High
Sarcoma 2 98.02 Very High Very High Very High
Chordoma 2 97.56 Very High Very High Very High
Generaliased Trisomy 2 97.52 Very High Very High Very High
Synovial Sarcoma 2 97.36 Very High Very High Very High
Amputation 4 95.28 Very High Very High Very High
Carcinoma 2 89.52 High High
Cancer 16 87.00 High High
Monostotic Fibrous Dysplasia 2 86.68 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
According to a study on the antibodies against a subtype of cytokeratin by Hazelbag et al, cytokeratin (CK) in AD is different from synovial sarcoma, chordoma, or epithelial sarcoma.13 Benassi et al. insisted on a correlation between OFD and AD based on their results that showed positive CK19 and negative CK8 and CK18 staining in both OFD and AD cases.12 In a cytogenetic study, both OFD and AD have trisomies on chromosomes 7, 8, and 12.4,16
Positive_regulation (positive) of Neg (negative) Gene_expression (staining) of OFD associated with sarcoma, adamantinoma, cleidocranial dysplasia, synovial sarcoma, generaliased trisomy and chordoma
1) Confidence 0.27 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628088 Disease Relevance 3.11 Pain Relevance 0
Some recent reports have suggested that OFD is a precursor of a neoplastic process leading to AD,1-4 and others have suggested that OFD is a residue of spontaneously regressing AD.5-7
Positive_regulation (suggested) of Gene_expression (residue) of OFD associated with adamantinoma and cleidocranial dysplasia
2) Confidence 0.27 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628088 Disease Relevance 1.94 Pain Relevance 0

General Comments

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