INT259012

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.27
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 6
Disease Relevance 2.82
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNFSF18) extracellular space (TNFSF18) plasma membrane (TNFSF18)
cell-cell signaling (TNFSF18)
Anatomy Link Frequency
blood 2
TNFSF18 (Homo sapiens)
Pain Link Frequency Relevance Heat
Sciatica 18 64.96 Quite High
imagery 6 48.24 Quite Low
Inflammatory response 6 38.48 Quite Low
backache 6 35.84 Quite Low
Cauda equina syndrome 6 31.20 Quite Low
Inflammation 18 13.52 Low Low
cytokine 24 7.68 Low Low
metalloproteinase 6 7.16 Low Low
Disease Link Frequency Relevance Heat
Intervertebral Disk Displacement 54 99.84 Very High Very High Very High
Autoimmune Disease 60 95.04 Very High Very High Very High
Disease Progression 6 89.84 High High
Necrosis 30 85.56 High High
Cancer 30 85.20 High High
Spinal Fractures 24 84.28 Quite High
Nerve Root Compression 18 64.96 Quite High
Injury 6 39.16 Quite Low
INFLAMMATION 24 38.12 Quite Low
Low Back Pain 6 35.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The purpose of the present study is to investigate whether the overexpression of AITR and AITRL might be associated with lumbar disc herniation.


Positive_regulation (overexpression) of Gene_expression (overexpression) of AITRL
1) Confidence 0.27 Published 2007 Journal Yonsei Medical Journal Section Abstract Doc Link PMC2628152 Disease Relevance 0.68 Pain Relevance 0
This phenomenon was not observed in healthy control groups, suggesting that the increased expression of AITR and AITRL might play a specific pathogenic role in lumbar disc herniation.
Positive_regulation (increased) of Gene_expression (expression) of AITRL
2) Confidence 0.24 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628152 Disease Relevance 0.41 Pain Relevance 0
This may be the first study to demonstrate that patients with lumbar disc herniation have a significantly increased AITR and AITRL expression in herniated disc tissue and in peripheral blood.
Positive_regulation (increased) of Gene_expression (expression) of AITRL in blood associated with intervertebral disk displacement
3) Confidence 0.20 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628152 Disease Relevance 0.42 Pain Relevance 0
The AITRL expression levels were also increased in patients with lumbar disc herniation, shown by using confocal laser scanning microscopy, immunohistochemistry and RT-PCR.
Positive_regulation (increased) of Gene_expression (expression) of AITRL
4) Confidence 0.18 Published 2007 Journal Yonsei Medical Journal Section Abstract Doc Link PMC2628152 Disease Relevance 0.45 Pain Relevance 0
The purpose of the present study is to determine if AITR and AITRL are overexpressed in symptomatic lumbar disc herniation patients.


Positive_regulation (overexpressed) of Gene_expression (overexpressed) of AITRL
5) Confidence 0.17 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628152 Disease Relevance 0.66 Pain Relevance 0.06
There was increased expression of AITRL and slightly increased expression of AITR on the herniated disc cells, but not in the controls (Fig. 6).
Positive_regulation (increased) of Gene_expression (expression) of AITRL associated with intervertebral disk displacement
6) Confidence 0.16 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628152 Disease Relevance 0.19 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox