INT259016

Context Info Confidence 0.06 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.67 Pain Relevance 0

plasma membrane (TNFSF18, Relt) signal transduction (TNFSF18) extracellular space (TNFSF18) molecular_function (Relt) cellular_component (Relt) cytoplasm (Relt)

TNFSF18 (Homo sapiens) Relt (Mus musculus)

Pain Link Frequency Relevance Heat cytokine 4 5.00 Inflammation 3 5.00 Sciatica 3 5.00 Inflammatory response 1 5.00 backache 1 5.00 Cauda equina syndrome 1 5.00 metalloproteinase 1 5.00 imagery 1 5.00

Disease Link Frequency Relevance Heat Necrosis 5 100.00 Cancer 5 100.00 Autoimmune Disease 10 97.48 Intervertebral Disk Displacement 9 83.68 Spinal Fractures 4 53.84 INFLAMMATION 4 5.00 Nerve Root Compression 3 5.00 Polyradiculopathy 1 5.00 Low Back Pain 1 5.00 Injury 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Human activation-inducible tumor necrosis factor receptor (AITR) and its ligand, AITRL, are important costimulatory molecules in the pathogenesis of autoimmune diseases.

Positive_regulation (inducible) of AITRL Binding (ligand) of tumor necrosis factor receptor associated with necrosis, autoimmune disease and cancer

1) Confidence 0.06 Published 2007 Journal Yonsei Medical Journal Section Abstract Doc Link PMC2628152 Disease Relevance 0.67 Pain Relevance 0

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