INT259116

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Context Info
Confidence 0.44
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 3.77
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (BRCA1) chromosome segregation (BRCA1) intracellular (BRCA1)
enzyme binding (BRCA1) DNA binding (BRCA1) protein complex (BRCA1)
BRCA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 74 50.00 Quite Low
Central nervous system 36 37.84 Quite Low
cytokine 72 5.00 Very Low Very Low Very Low
Inflammatory response 12 5.00 Very Low Very Low Very Low
Neuritis 4 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
depression 3 5.00 Very Low Very Low Very Low
Inflammatory marker 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Immune Reconstitution Inflammatory Syndrome 444 100.00 Very High Very High Very High
Aggression 85 100.00 Very High Very High Very High
Cryptococcal Meningitis 204 99.98 Very High Very High Very High
Breast Cancer 10 99.10 Very High Very High Very High
Cancer 42 98.60 Very High Very High Very High
Hyperplasia 1 85.28 High High
Death 36 80.48 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 96 75.36 Quite High
Mouth Cancer 1 54.00 Quite High
Cleidocranial Dysplasia 3 48.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This protocol describes IRIS, a pragmatic cluster randomised controlled trial with the general practice as unit of randomisation.
Transcription (describes) of IRIS associated with aggression
1) Confidence 0.44 Published 2010 Journal BMC Public Health Section Abstract Doc Link PMC2825222 Disease Relevance 0.62 Pain Relevance 0
Additionally, Sum et al [19] found that LMO4 interacts with the cofactor CtIP and the tumor suppressor breast cancer 1 (BRCA1), and inhibits the transcriptional activity of BRCA1 in both yeast and mammalian cells by functional assays.
Transcription (activity) of BRCA1 associated with cancer and breast cancer
2) Confidence 0.23 Published 2008 Journal Mol Cancer Section Body Doc Link PMC2628350 Disease Relevance 0.70 Pain Relevance 0
Among persons experiencing CM-IRIS, mortality after an IRIS event was associated with increased IL-10 levels (OR?
Transcription (mortality) of IRIS associated with cryptococcal meningitis and immune reconstitution inflammatory syndrome
3) Confidence 0.12 Published 2010 Journal PLoS Medicine Section Body Doc Link PMC3014618 Disease Relevance 1.22 Pain Relevance 0
Among persons experiencing CM-IRIS, mortality after an IRIS event was associated with increased IL-10 levels (OR?
Transcription (mortality) of IRIS associated with cryptococcal meningitis and immune reconstitution inflammatory syndrome
4) Confidence 0.12 Published 2010 Journal PLoS Medicine Section Body Doc Link PMC3014618 Disease Relevance 1.23 Pain Relevance 0

General Comments

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