INT259139

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Context Info
Confidence 0.44
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.89
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (DSG2) plasma membrane (DSG2)
DSG2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 15 80.84 Quite High
Inflammation 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
nud 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stomach Cancer 65 100.00 Very High Very High Very High
Pancreatic Cancer 38 100.00 Very High Very High Very High
Cancer 37 98.16 Very High Very High Very High
Adenocarcinoma 16 93.60 High High
Pancreatitis 17 80.84 Quite High
Linitis Plastica 1 56.48 Quite High
Syndrome 2 52.96 Quite High
Carcinoma 19 31.72 Quite Low
Breast Cancer 10 12.24 Low Low
Adhesions 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The correspondence between increased hK7 expression in pancreatic tumors and loss of Dsg2 is highlighted in the immunohistochemistry studies we have performed.
Positive_regulation (increased) of Gene_expression (expression) of Dsg2 associated with pancreatic cancer
1) Confidence 0.44 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2628383 Disease Relevance 0.89 Pain Relevance 0.21
Increasing awareness of HDGC and the rapid advances in genetic diagnostic tools, endoscopic modalities and the increasing use of laparoscopic surgery led a group of clinical geneticists, gastroenterologists, surgeons, oncologists, pathologists and molecular biologists from nine different countries to convene a workshop in order to update the management guidelines for this condition originally set in 1999 and to propose directions for future research.
Positive_regulation (Increasing) of Gene_expression (awareness) of HDGC associated with stomach cancer
2) Confidence 0.13 Published 2010 Journal Journal of Medical Genetics Section Body Doc Link PMC2991043 Disease Relevance 1.00 Pain Relevance 0

General Comments

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