INT259150

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Context Info
Confidence 0.67
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.32
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (DSG2) plasma membrane (DSG2)
DSG2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 30 91.24 High High
Inflammation 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
nud 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stomach Cancer 67 100.00 Very High Very High Very High
Pancreatitis 34 91.24 High High
Adhesions 24 90.16 High High
Adenocarcinoma 30 88.76 High High
Pancreatic Cancer 76 87.20 High High
Breast Cancer 10 35.76 Quite Low
Cancer 57 5.00 Very Low Very Low Very Low
Carcinoma 20 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 13 5.00 Very Low Very Low Very Low
Metastasis 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When hK7 was overexpressed in this cell line, there was a significant increase in the amount of soluble Dsg2 released into the culture medium compared with vector-transfected control cells.


Localization (released) of Dsg2
1) Confidence 0.67 Published 2008 Journal BMC Cancer Section Abstract Doc Link PMC2628383 Disease Relevance 0.70 Pain Relevance 0.09
The amount of sDsg2 released into the conditioned medium of each sample was quantified using Quantity One image analysis software.
Localization (released) of sDsg2
2) Confidence 0.58 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2628383 Disease Relevance 0.25 Pain Relevance 0.13
It is critical that families who meet clinical criteria for HDGC, but do not carry an identifiable CDH1 mutation or who carry a CDH1 variant that does not result in a truncated protein, are registered for clinical research studies.
Localization (mutation) of HDGC associated with stomach cancer
3) Confidence 0.23 Published 2010 Journal Journal of Medical Genetics Section Body Doc Link PMC2991043 Disease Relevance 0.37 Pain Relevance 0

General Comments

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