INT259171

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Context Info
Confidence 0.76
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.48
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gria1) endoplasmic reticulum (Gria1) plasma membrane (Gria1)
protein complex (Gria1)
Anatomy Link Frequency
neurons 1
Gria1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 26 99.24 Very High Very High Very High
Dorsal horn neuron 13 99.12 Very High Very High Very High
Eae 29 96.12 Very High Very High Very High
Dorsal horn 21 94.68 High High
Spinal cord 21 53.40 Quite High
antagonist 27 32.88 Quite Low
Lasting pain 4 27.24 Quite Low
withdrawal 19 17.36 Low Low
intrathecal 11 9.20 Low Low
central sensitization 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 26 99.24 Very High Very High Very High
Inflammatory Pain 28 96.12 Very High Very High Very High
Nociception 10 55.28 Quite High
Hypersensitivity 16 36.28 Quite Low
Pain 7 27.24 Quite Low
Syndrome 1 10.00 Low Low
Sleep Disorders 1 7.16 Low Low
Neuropathic Pain 2 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is very likely that peripheral inflammatory insult does not alter translation of GluR1 and GluR2 genes and/or degradation of their proteins in dorsal horn neurons.
Protein_catabolism (degradation) of GluR1 in neurons associated with inflammation and dorsal horn neuron
1) Confidence 0.76 Published 2008 Journal Mol Pain Section Body Doc Link PMC2628655 Disease Relevance 0.48 Pain Relevance 0.58

General Comments

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