INT259208

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Creb1) mitochondrion (Creb1) lyase activity (Ca2)
DNA binding (Creb1) response to stress (Ca2) cytoplasm (Ca2)
Ca2 (Rattus norvegicus)
Creb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
narcan 67 80.72 Quite High
Morphine 76 78.56 Quite High
mu opioid receptor 97 61.92 Quite High
Opioid 42 50.00 Quite Low
addiction 17 5.00 Very Low Very Low Very Low
tolerance 13 5.00 Very Low Very Low Very Low
antagonist 5 5.00 Very Low Very Low Very Low
opiate 4 5.00 Very Low Very Low Very Low
analgesia 3 5.00 Very Low Very Low Very Low
Nucleus accumbens 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Opiate Addiction 4 5.00 Very Low Very Low Very Low
Drug Dependence 2 5.00 Very Low Very Low Very Low
Bordatella Infection 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since CREB phosphorylation at the S133 can also be induced in response to elevated intracellular Ca2+, experiments were designed to assess the contribution of Ca2+ by including cell permeable intracellular Ca2+ chelator, BAPTA-AM.
Ca2 Positive_regulation (induced) of Phosphorylation (phosphorylation) of CREB
1) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2628740 Disease Relevance 0 Pain Relevance 0.45

General Comments

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