INT259219

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Context Info
Confidence 0.23
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Flna) plasma membrane (Flna) nucleus (Flna)
transcription factor binding (Flna) biological_process (Flna) cytoplasm (Flna)
Flna (Rattus norvegicus)
Pain Link Frequency Relevance Heat
mu opioid receptor 97 100.00 Very High Very High Very High
Morphine 76 100.00 Very High Very High Very High
narcan 67 99.96 Very High Very High Very High
antagonist 5 82.92 Quite High
Opioid 42 82.48 Quite High
addiction 17 65.44 Quite High
tolerance 13 64.84 Quite High
Analgesic 3 64.44 Quite High
opiate 4 57.80 Quite High
Oxycodone 3 21.72 Low Low
Disease Link Frequency Relevance Heat
Opiate Addiction 4 5.00 Very Low Very Low Very Low
Drug Dependence 2 5.00 Very Low Very Low Very Low
Bordatella Infection 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this prior study, FLNA peptides presumably bound to NLX, blocking its prevention of the morphine-induced MOR–Gs coupling by preventing it from binding full-length FLNA in the tissues.
Negative_regulation (blocking) of Negative_regulation (prevention) of FLNA associated with mu opioid receptor, narcan and morphine
1) Confidence 0.23 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2628740 Disease Relevance 0 Pain Relevance 1.47

General Comments

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