INT259220

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Context Info
Confidence 0.36
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.61
Pain Relevance 1.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Glul) mitochondrion (Glul) lyase activity (Glul)
Golgi apparatus (Glul) intracellular (Glul) protein complex (Glul)
Glul (Rattus norvegicus)
Pain Link Frequency Relevance Heat
mu opioid receptor 97 99.98 Very High Very High Very High
Morphine 98 99.74 Very High Very High Very High
narcan 70 98.92 Very High Very High Very High
Glutamate 23 87.60 High High
antagonist 6 80.84 Quite High
alcohol 1 80.68 Quite High
Opioid 42 80.40 Quite High
addiction 24 63.36 Quite High
tolerance 13 62.76 Quite High
Analgesic 3 62.36 Quite High
Disease Link Frequency Relevance Heat
Diabetes Mellitus 70 97.08 Very High Very High Very High
Decapitation 2 77.64 Quite High
Drug Dependence 6 77.48 Quite High
Death 17 35.32 Quite Low
Stress 16 33.12 Quite Low
INFLAMMATION 5 22.36 Low Low
Drug Induced Neurotoxicity 7 20.64 Low Low
Cv General 4 Under Development 1 12.12 Low Low
Ganglion Cysts 13 5.00 Very Low Very Low Very Low
Injury 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Glutamine synthetase assay
Glutamine synthetase Binding (assay) of
1) Confidence 0.36 Published 2010 Journal Anal Bioanal Chem Section Body Doc Link PMC2990007 Disease Relevance 0.08 Pain Relevance 0.29
Glutamine synthetase activity
Glutamine synthetase Binding (activity) of
2) Confidence 0.32 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2925907 Disease Relevance 0.53 Pain Relevance 0.12
In this prior study, FLNA peptides presumably bound to NLX, blocking its prevention of the morphine-induced MOR–Gs coupling by preventing it from binding full-length FLNA in the tissues.
Gs Binding (coupling) of associated with mu opioid receptor, narcan and morphine
3) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2628740 Disease Relevance 0 Pain Relevance 1.38

General Comments

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