INT259229

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transducer activity (Oprm1, Flna) plasma membrane (Oprm1, Flna) cytoplasm (Flna)
cytosol (Flna) signal transduction (Oprm1) nucleus (Flna)
Oprm1 (Mus musculus)
Flna (Rattus norvegicus)
Pain Link Frequency Relevance Heat
mu opioid receptor 97 100.00 Very High Very High Very High
narcan 67 96.92 Very High Very High Very High
Morphine 76 92.48 High High
Opioid 42 87.64 High High
addiction 17 58.08 Quite High
tolerance 13 57.48 Quite High
antagonist 5 5.00 Very Low Very Low Very Low
opiate 4 5.00 Very Low Very Low Very Low
analgesia 3 5.00 Very Low Very Low Very Low
Nucleus accumbens 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Opiate Addiction 4 5.00 Very Low Very Low Very Low
Drug Dependence 2 5.00 Very Low Very Low Very Low
Bordatella Infection 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We propose that acute, robust stimulation of MOR causes an interaction with FLNA that allows an initially transient MOR–Gs coupling, which recovers with receptor recycling but persists when MOR stimulation is repeated or prolonged.
Positive_regulation (causes) of MOR Binding (interaction) of FLNA associated with mu opioid receptor
1) Confidence 0.02 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2628740 Disease Relevance 0 Pain Relevance 1.23

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox