INT259232

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Flna, Oprm1) signal transducer activity (Flna, Oprm1) cytosol (Flna)
signal transduction (Oprm1) nucleus (Flna) transcription factor binding (Flna)
Flna (Rattus norvegicus)
Oprm1 (Mus musculus)
Pain Link Frequency Relevance Heat
mu opioid receptor 97 100.00 Very High Very High Very High
Morphine 76 88.40 High High
narcan 67 86.76 High High
tolerance 13 75.76 Quite High
addiction 17 74.88 Quite High
opiate 4 71.68 Quite High
antagonist 5 69.76 Quite High
Opioid 42 69.32 Quite High
Analgesic 3 51.28 Quite High
Oxycodone 3 8.56 Low Low
Disease Link Frequency Relevance Heat
Opiate Addiction 4 5.00 Very Low Very Low Very Low
Drug Dependence 2 5.00 Very Low Very Low Very Low
Bordatella Infection 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We theorized that a particular FLNA–MOR interaction enables MOR to release from the signaling complex to couple to Gs upon subsequent receptor stimulation.
FLNA Binding (interaction) of Positive_regulation (enables) of Localization (release) of MOR associated with mu opioid receptor
1) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2628740 Disease Relevance 0 Pain Relevance 1.39

General Comments

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