INT259556

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Context Info
Confidence 0.46
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.15
Pain Relevance 0.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (PLEK, VEGFA) cytoplasm (PLEK, VEGFA) cytosol (PLEK)
extracellular space (VEGFA) growth (VEGFA) proteinaceous extracellular matrix (VEGFA)
Anatomy Link Frequency
platelet 4
PLEK (Homo sapiens)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
corticosteroid 8 99.88 Very High Very High Very High
Inflammation 8 97.72 Very High Very High Very High
cva 50 66.20 Quite High
lidocaine 2 5.00 Very Low Very Low Very Low
iatrogenic 2 5.00 Very Low Very Low Very Low
Perioperative pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 2 97.90 Very High Very High Very High
INFLAMMATION 8 97.72 Very High Very High Very High
Retinal Diseases 2 90.56 High High
Diabetic Retinopathy 10 88.24 High High
Disease 2 87.56 High High
Age-related Macular Degeneration 2 82.96 Quite High
Ocular Injury 46 66.20 Quite High
Diabetes Mellitus 16 65.44 Quite High
Cataract 6 34.96 Quite Low
Retina Disease 4 26.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Corticosteroids inhibit rostaglandins and inflammatory adhesion molecules, thus contribute to the stabilization of the blood-retinal barrier.13-15 Corticosteroids also inhibit expression of the vascular endothelial growth factor (VEGF), as well as the induction of VEGF by platelet-derived growth factor (PEGF) and platelet activating factor (PAF).16
platelet Negative_regulation (inhibit) of Gene_expression (expression) of VEGF in platelet associated with corticosteroid, inflammation and adhesions
1) Confidence 0.46 Published 2007 Journal Korean Journal of Ophthalmology : KJO Section Body Doc Link PMC2629885 Disease Relevance 1.07 Pain Relevance 0.36
Corticosteroids inhibit rostaglandins and inflammatory adhesion molecules, thus contribute to the stabilization of the blood-retinal barrier.13-15 Corticosteroids also inhibit expression of the vascular endothelial growth factor (VEGF), as well as the induction of VEGF by platelet-derived growth factor (PEGF) and platelet activating factor (PAF).16
platelet Negative_regulation (inhibit) of Gene_expression (expression) of vascular endothelial growth factor in platelet associated with corticosteroid, inflammation and adhesions
2) Confidence 0.46 Published 2007 Journal Korean Journal of Ophthalmology : KJO Section Body Doc Link PMC2629885 Disease Relevance 1.07 Pain Relevance 0.36

General Comments

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